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Age-Related Changes in Global Motion Coherence: Conflicting Haemodynamic and Perceptual Responses
Our aim was to use both behavioural and neuroimaging data to identify indicators of perceptual decline in motion processing. We employed a global motion coherence task and functional Near Infrared Spectroscopy (fNIRS). Healthy adults (n = 72, 18–85) were recruited into the following groups: young (n...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030110/ https://www.ncbi.nlm.nih.gov/pubmed/29968729 http://dx.doi.org/10.1038/s41598-018-27803-5 |
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author | Ward, Laura McKernan Morison, Gordon Simmers, Anita Jane Shahani, Uma |
author_facet | Ward, Laura McKernan Morison, Gordon Simmers, Anita Jane Shahani, Uma |
author_sort | Ward, Laura McKernan |
collection | PubMed |
description | Our aim was to use both behavioural and neuroimaging data to identify indicators of perceptual decline in motion processing. We employed a global motion coherence task and functional Near Infrared Spectroscopy (fNIRS). Healthy adults (n = 72, 18–85) were recruited into the following groups: young (n = 28, mean age = 28), middle-aged (n = 22, mean age = 50), and older adults (n = 23, mean age = 70). Participants were assessed on their motion coherence thresholds at 3 different speeds using a psychophysical design. As expected, we report age group differences in motion processing as demonstrated by higher motion coherence thresholds in older adults. Crucially, we add correlational data showing that global motion perception declines linearly as a function of age. The associated fNIRS recordings provide a clear physiological correlate of global motion perception. The crux of this study lies in the robust linear correlation between age and haemodynamic response for both measures of oxygenation. We hypothesise that there is an increase in neural recruitment, necessitating an increase in metabolic need and blood flow, which presents as a higher oxygenated haemoglobin response. We report age-related changes in motion perception with poorer behavioural performance (high motion coherence thresholds) associated with an increased haemodynamic response. |
format | Online Article Text |
id | pubmed-6030110 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-60301102018-07-11 Age-Related Changes in Global Motion Coherence: Conflicting Haemodynamic and Perceptual Responses Ward, Laura McKernan Morison, Gordon Simmers, Anita Jane Shahani, Uma Sci Rep Article Our aim was to use both behavioural and neuroimaging data to identify indicators of perceptual decline in motion processing. We employed a global motion coherence task and functional Near Infrared Spectroscopy (fNIRS). Healthy adults (n = 72, 18–85) were recruited into the following groups: young (n = 28, mean age = 28), middle-aged (n = 22, mean age = 50), and older adults (n = 23, mean age = 70). Participants were assessed on their motion coherence thresholds at 3 different speeds using a psychophysical design. As expected, we report age group differences in motion processing as demonstrated by higher motion coherence thresholds in older adults. Crucially, we add correlational data showing that global motion perception declines linearly as a function of age. The associated fNIRS recordings provide a clear physiological correlate of global motion perception. The crux of this study lies in the robust linear correlation between age and haemodynamic response for both measures of oxygenation. We hypothesise that there is an increase in neural recruitment, necessitating an increase in metabolic need and blood flow, which presents as a higher oxygenated haemoglobin response. We report age-related changes in motion perception with poorer behavioural performance (high motion coherence thresholds) associated with an increased haemodynamic response. Nature Publishing Group UK 2018-07-03 /pmc/articles/PMC6030110/ /pubmed/29968729 http://dx.doi.org/10.1038/s41598-018-27803-5 Text en © The Author(s) 2018 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Ward, Laura McKernan Morison, Gordon Simmers, Anita Jane Shahani, Uma Age-Related Changes in Global Motion Coherence: Conflicting Haemodynamic and Perceptual Responses |
title | Age-Related Changes in Global Motion Coherence: Conflicting Haemodynamic and Perceptual Responses |
title_full | Age-Related Changes in Global Motion Coherence: Conflicting Haemodynamic and Perceptual Responses |
title_fullStr | Age-Related Changes in Global Motion Coherence: Conflicting Haemodynamic and Perceptual Responses |
title_full_unstemmed | Age-Related Changes in Global Motion Coherence: Conflicting Haemodynamic and Perceptual Responses |
title_short | Age-Related Changes in Global Motion Coherence: Conflicting Haemodynamic and Perceptual Responses |
title_sort | age-related changes in global motion coherence: conflicting haemodynamic and perceptual responses |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030110/ https://www.ncbi.nlm.nih.gov/pubmed/29968729 http://dx.doi.org/10.1038/s41598-018-27803-5 |
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