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LIM kinase1 regulates mitotic centrosome integrity via its activity on dynein light intermediate chains

Abnormal centrosome number and function have been implicated in tumour development. LIM kinase1 (LIMK1), a regulator of actin cytoskeleton dynamics, is found to localize at the mitotic centrosome. However, its role at the centrosome is not fully explored. Here, we report that LIMK1 depletion resulte...

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Detalles Bibliográficos
Autores principales:	Ou, Sirong, Tan, Mei-Hua, Weng, Ting, Li, HoiYeung, Koh, Cheng-Gee
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030115/ https://www.ncbi.nlm.nih.gov/pubmed/29925632 http://dx.doi.org/10.1098/rsob.170202

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