Consequences of blunting the mevalonate pathway in cancer identified by a pluri-omics approach

We have previously shown that the combination of statins and taxanes was a powerful trigger of HGT-1 human gastric cancer cells’ apoptosis(1). Importantly, several genes involved in the “Central carbon metabolism pathway in cancer”, as reported in the Kyoto Encyclopedia of Genes and Genomes, were ei...

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Detalles Bibliográficos
Autores principales: Goulitquer, Sophie, Croyal, Mikaël, Lalande, Julie, Royer, Anne-Lise, Guitton, Yann, Arzur, Danielle, Durand, Stéphanie, Le Jossic-Corcos, Catherine, Bouchereau, Alain, Potin, Philippe, Akoka, Serge, Antignac, Jean-Philippe, Krempf, Michel, Ferchaud-Roucher, Véronique, Giraudeau, Patrick, Corcos, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030166/
https://www.ncbi.nlm.nih.gov/pubmed/29970880
http://dx.doi.org/10.1038/s41419-018-0761-0

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