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Intradermal injection of low dose human regulatory T cells inhibits skin inflammation in a humanized mouse model
Recent regulatory T cell (Treg) based clinical trials support their therapeutic potential in transplantation and auto-inflammatory diseases. However, large numbers of Treg are needed to accomplish therapeutic efficacy. Local injection at the site of inflammation (targeted delivery) may lower the num...
Autores principales: | Landman, Sija, de Oliveira, Vivian L., van Erp, Piet E. J., Fasse, Esther, Bauland, Stijn C. G., Joosten, Irma, Koenen, Hans J. P. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030170/ https://www.ncbi.nlm.nih.gov/pubmed/29968819 http://dx.doi.org/10.1038/s41598-018-28346-5 |
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