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Complex spectrum of phenobarbital effects in a mouse model of neonatal hypoxia-induced seizures
Seizures in neonates, mainly caused by hypoxic-ischemic encephalopathy, are thought to be harmful to the brain. Phenobarbital remains the first line drug therapy for the treatment of suspected neonatal seizures but concerns remain with efficacy and safety. Here we explored the short- and long-term o...
Autores principales: | Quinlan, Sean M. M., Rodriguez-Alvarez, Natalia, Molloy, Eleanor J., Madden, Stephen F., Boylan, Geraldine B., Henshall, David C., Jimenez-Mateos, Eva M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030182/ https://www.ncbi.nlm.nih.gov/pubmed/29968748 http://dx.doi.org/10.1038/s41598-018-28044-2 |
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