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Substitution of Mannan-Binding Lectin (MBL)-Deficient Serum With Recombinant MBL Results in the Formation of New MBL/MBL-Associated Serine Protease Complexes

The lectin pathway (LP) of complement activation depends on the activation of the MBL-associated serine proteases (MASPs) circulating in complex with mannan-binding lectin (MBL). MBL deficiency is the most common complement deficiency and has been associated with several pathological conditions. As...

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Detalles Bibliográficos
Autores principales:	Keizer, Mischa P., Kamp, Angela, van Mierlo, Gerard, Kuijpers, Taco W., Wouters, Diana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030254/ https://www.ncbi.nlm.nih.gov/pubmed/29997613 http://dx.doi.org/10.3389/fimmu.2018.01406

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