Kruppel-Like Factor 4 Positively Regulates Autoimmune Arthritis in Mouse Models and Rheumatoid Arthritis in Patients via Modulating Cell Survival and Inflammation Factors of Fibroblast-Like Synoviocyte

Rheumatoid arthritis (RA) is a chronic autoimmune disease that causes mild to severe joint inflammation. During RA pathogenesis, fibroblast-like synoviocytes (FLS) acquire a tumor-like phenotype and mediate cartilage destruction both directly and indirectly by producing proinflammatory cytokines and...

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Detalles Bibliográficos
Autores principales: Choi, Seungjin, Lee, Kijun, Jung, Hyerin, Park, Narae, Kang, Jaewoo, Nam, Ki-Hoan, Kim, Eun-Kyeong, Ju, Ji Hyeon, Kang, Kwi Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030377/
https://www.ncbi.nlm.nih.gov/pubmed/29997611
http://dx.doi.org/10.3389/fimmu.2018.01339

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