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BRCA1 Mutation Status and Follicular Fluid Exposure Alters NFκB Signaling and ISGylation in Human Fallopian Tube Epithelial Cells()()

Germline BRCA1 or BRCA2 mutations (mtBRCA1 and mtBRCA2) increase risk for high-grade serous ovarian cancer (HGSOC), the most commonly diagnosed epithelial ovarian cancer histotype. Other identified risk factors for this cancer, which originates primarily in the distal fallopian tube epithelium (FTE)...

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Detalles Bibliográficos
Autores principales: Hollingsworth, Julia, Lau, Angela, Tone, Alicia, Kollara, Alexandra, Allen, Lisa, Colgan, Terence J., Dube, Valerie, Rosen, Barry, Murphy, K. Joan, Greenblatt, Ellen M., Feigenberg, Tomer, Virtanen, Carl, Brown, Theodore J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030391/
https://www.ncbi.nlm.nih.gov/pubmed/29852322
http://dx.doi.org/10.1016/j.neo.2018.05.005