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BRCA1 Mutation Status and Follicular Fluid Exposure Alters NFκB Signaling and ISGylation in Human Fallopian Tube Epithelial Cells()()
Germline BRCA1 or BRCA2 mutations (mtBRCA1 and mtBRCA2) increase risk for high-grade serous ovarian cancer (HGSOC), the most commonly diagnosed epithelial ovarian cancer histotype. Other identified risk factors for this cancer, which originates primarily in the distal fallopian tube epithelium (FTE)...
Autores principales: | Hollingsworth, Julia, Lau, Angela, Tone, Alicia, Kollara, Alexandra, Allen, Lisa, Colgan, Terence J., Dube, Valerie, Rosen, Barry, Murphy, K. Joan, Greenblatt, Ellen M., Feigenberg, Tomer, Virtanen, Carl, Brown, Theodore J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030391/ https://www.ncbi.nlm.nih.gov/pubmed/29852322 http://dx.doi.org/10.1016/j.neo.2018.05.005 |
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