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Tumor-Specific Mitochondrial DNA Variants Are Rarely Detected in Cell-Free DNA()()

The use of blood-circulating cell-free DNA (cfDNA) as a “liquid biopsy” in oncology is being explored for its potential as a cancer biomarker. Mitochondria contain their own circular genomic entity (mitochondrial DNA, mtDNA), up to even thousands of copies per cell. The mutation rate of mtDNA is sev...

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Detalles Bibliográficos
Autores principales:	Weerts, M.J.A., Timmermans, E.C., van de Stolpe, A., Vossen, R.H.A.M., Anvar, S.Y., Foekens, J.A., Sleijfer, S., Martens, J.W.M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Neoplasia Press 2018
Materias:	Original article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030393/ https://www.ncbi.nlm.nih.gov/pubmed/29842994 http://dx.doi.org/10.1016/j.neo.2018.05.003

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