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Association between maternal HIV disclosure and risk factors for perinatal transmission
OBJECTIVE: To determine whether maternal disclosure of HIV serostatus is associated with uptake of perinatal HIV transmission prevention interventions. STUDY DESIGN: Retrospective cohort study of women living with HIV enrolled in a perinatal HIV clinic. Women who disclosed their HIV serostatus to se...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030432/ https://www.ncbi.nlm.nih.gov/pubmed/29434253 http://dx.doi.org/10.1038/s41372-018-0066-2 |
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author | Yee, Lynn M McGregor, Donna V Sutton, Sarah H Garcia, Patricia M Miller, Emily S |
author_facet | Yee, Lynn M McGregor, Donna V Sutton, Sarah H Garcia, Patricia M Miller, Emily S |
author_sort | Yee, Lynn M |
collection | PubMed |
description | OBJECTIVE: To determine whether maternal disclosure of HIV serostatus is associated with uptake of perinatal HIV transmission prevention interventions. STUDY DESIGN: Retrospective cohort study of women living with HIV enrolled in a perinatal HIV clinic. Women who disclosed their HIV serostatus to sexual partner(s) prior to delivery were compared to non-disclosers. Multivariable logistic regression was performed. RESULTS: Of 209 women, 71.3% (N=149) disclosed. Non-disclosers were more likely to attend <10 prenatal visits, demonstrated worse antiretroviral therapy adherence, required more time to achieve virologic suppression, and were less likely to have an undetectable viral load. On multivariable analyses, disclosure status did not remain associated with these factors. However, compared to non-disclosers, disclosers had lower odds of preterm delivery (OR 0.43, 95% CI 0.19–0.94) and greater odds of postpartum visit attendance (aOR 5.10, 95% CI 1.65–15.72). CONCLUSIONS: Non-disclosure of HIV status to sexual partner(s) during pregnancy may be a risk factor for preterm birth and poorer postpartum visit attendance. |
format | Online Article Text |
id | pubmed-6030432 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
record_format | MEDLINE/PubMed |
spelling | pubmed-60304322018-08-12 Association between maternal HIV disclosure and risk factors for perinatal transmission Yee, Lynn M McGregor, Donna V Sutton, Sarah H Garcia, Patricia M Miller, Emily S J Perinatol Article OBJECTIVE: To determine whether maternal disclosure of HIV serostatus is associated with uptake of perinatal HIV transmission prevention interventions. STUDY DESIGN: Retrospective cohort study of women living with HIV enrolled in a perinatal HIV clinic. Women who disclosed their HIV serostatus to sexual partner(s) prior to delivery were compared to non-disclosers. Multivariable logistic regression was performed. RESULTS: Of 209 women, 71.3% (N=149) disclosed. Non-disclosers were more likely to attend <10 prenatal visits, demonstrated worse antiretroviral therapy adherence, required more time to achieve virologic suppression, and were less likely to have an undetectable viral load. On multivariable analyses, disclosure status did not remain associated with these factors. However, compared to non-disclosers, disclosers had lower odds of preterm delivery (OR 0.43, 95% CI 0.19–0.94) and greater odds of postpartum visit attendance (aOR 5.10, 95% CI 1.65–15.72). CONCLUSIONS: Non-disclosure of HIV status to sexual partner(s) during pregnancy may be a risk factor for preterm birth and poorer postpartum visit attendance. 2018-02-12 2018-06 /pmc/articles/PMC6030432/ /pubmed/29434253 http://dx.doi.org/10.1038/s41372-018-0066-2 Text en Users may view, print, copy, and download text and data-mine the content in such documents, for the purposes of academic research, subject always to the full Conditions of use: http://www.nature.com/authors/editorial_policies/license.html#terms |
spellingShingle | Article Yee, Lynn M McGregor, Donna V Sutton, Sarah H Garcia, Patricia M Miller, Emily S Association between maternal HIV disclosure and risk factors for perinatal transmission |
title | Association between maternal HIV disclosure and risk factors for perinatal transmission |
title_full | Association between maternal HIV disclosure and risk factors for perinatal transmission |
title_fullStr | Association between maternal HIV disclosure and risk factors for perinatal transmission |
title_full_unstemmed | Association between maternal HIV disclosure and risk factors for perinatal transmission |
title_short | Association between maternal HIV disclosure and risk factors for perinatal transmission |
title_sort | association between maternal hiv disclosure and risk factors for perinatal transmission |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030432/ https://www.ncbi.nlm.nih.gov/pubmed/29434253 http://dx.doi.org/10.1038/s41372-018-0066-2 |
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