Cargando…
Alteration in Nerves and Neurotransmitter Stimulation of Lacrimal Gland Secretion in the TSP-1(−/−) Mouse Model of Aqueous Deficiency Dry Eye
The purpose of this study is to determine neural, vascular, protein secretion, and cellular signaling changes with disease progression in lacrimal glands of the thrombospondin-1(−/−) (TSP-1(−/−)) mouse model of dry eye compared to C57BL/6 wild type (WT) mice. Neural innervation was reduced in TSP-1(...
Autores principales: | Bhattacharya, Sumit, Garcia-Posadas, Laura, Hodges, Robin R., Makarenkova, Helen P., Masli, Sharmila, Dartt, Darlene A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030454/ https://www.ncbi.nlm.nih.gov/pubmed/29445135 http://dx.doi.org/10.1038/s41385-018-0002-y |
Ejemplares similares
-
Lacrimal Gland Repair Using Progenitor Cells
por: Gromova, Anastasia, et al.
Publicado: (2016) -
Spatial transcriptomics of the lacrimal gland features macrophage activity and epithelium metabolism as key alterations during chronic inflammation
por: Mauduit, Olivier, et al.
Publicado: (2022) -
Mouse Models of Sjögren’s Syndrome with Ocular Surface Disease
por: Masli, Sharmila, et al.
Publicado: (2020) -
Lacrimal Gland Epithelial Cells Shape Immune Responses through the Modulation of Inflammasomes and Lipid Metabolism
por: Delcroix, Vanessa, et al.
Publicado: (2023) -
Lacrimal Gland, Ocular Surface, and Dry Eye
por: Ding, Chuanqing, et al.
Publicado: (2016)