Cargando…

B cells are the predominant mediators of early systemic viral dissemination during rectal LCMV infection

Determining the magnitude of local immune response during mucosal exposure to viral pathogens is critical to understanding the mechanism of viral pathogenesis. We previously showed that vaginal inoculation of lymphocytic choriomeningitis virus (LCMV) fails to induce a robust innate immune response i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Trapecar, Martin, Khan, Shahzada, Cohn, Benjamin L., Wu, Frank, Sanjabi, Shomyseh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030459/ https://www.ncbi.nlm.nih.gov/pubmed/29456247 http://dx.doi.org/10.1038/s41385-018-0009-4

Ejemplares similares

Dampened antiviral immunity to intravaginal exposure to RNA viral pathogens allows enhanced viral replication
por: Khan, Shahzada, et al.
Publicado: (2016)

Low expression of RNA sensors impacts Zika virus infection in the lower female reproductive tract
por: Khan, Shahzada, et al.
Publicado: (2019)

LCMV Glycosylation Modulates Viral Fitness and Cell Tropism
por: Bonhomme, Cyrille J., et al.
Publicado: (2013)

Single cell genome sequencing of laboratory mouse microbiota improves taxonomic and functional resolution of this model microbial community
por: Lyalina, Svetlana, et al.
Publicado: (2022)

Difference of two new LCMV strains in lethality and viral genome load in tissues
por: Takagi, Toshikazu, et al.
Publicado: (2017)

Viral Infections and Autoimmune Disease: Roles of LCMV in Delineating Mechanisms of Immune Tolerance
por: Fousteri, Georgia, et al.
Publicado: (2019)

Increased HIV-1 transcriptional activity and infectious burden in peripheral blood and gut-associated CD4(+) T cells expressing CD30
por: Hogan, Louise E., et al.
Publicado: (2018)

Role of Lymphocytic Choriomeningitis Virus (LCMV) in Understanding Viral Immunology: Past, Present and Future
por: Zhou, Xin, et al.
Publicado: (2012)

Viruses Teaching Immunology: Role of LCMV Model and Human Viral Infections in Immunological Discoveries
por: Abdel-Hakeem, Mohamed S.
Publicado: (2019)

Sugar or Fat?—Metabolic Requirements for Immunity to Viral Infections
por: Shehata, Hesham M., et al.
Publicado: (2017)

B cell–derived IL-27 promotes control of persistent LCMV infection
por: Pratumchai, Isaraphorn, et al.
Publicado: (2022)

Replication-incompetent rabies virus vector harboring glycoprotein gene of lymphocytic choriomeningitis virus (LCMV) protects mice from LCMV challenge
por: Takayama-Ito, Mutsuyo, et al.
Publicado: (2018)

Visualization of the lymphocytic choriomeningitis mammarenavirus (LCMV) genome reveals the early endosome as a possible site for genome replication and viral particle  pre-assembly
por: King, Benjamin R., et al.
Publicado: (2017)

CNS activity of Pokeweed Anti-viral Protein (PAP) in mice infected with Lymphocytic Choriomeningitis Virus (LCMV)
por: Uckun, Fatih M, et al.
Publicado: (2005)

Chronic LCMV Infection Is Fortified with Versatile Tactics to Suppress Host T Cell Immunity and Establish Viral Persistence
por: Studstill, Caleb J., et al.
Publicado: (2021)

The LCMV gp33-specific memory T cell repertoire narrows with age
por: Bunztman, Adam, et al.
Publicado: (2012)

LCMV‐specific CD4 T cell dependent polyclonal B‐cell activation upon persistent viral infection is short lived and extrafollicular
por: Greczmiel, Ute, et al.
Publicado: (2019)

Targeted Deletion of FGL2 Leads to Increased Early Viral Replication and Enhanced Adaptive Immunity in a Murine Model of Acute Viral Hepatitis Caused by LCMV WE
por: Khattar, Ramzi, et al.
Publicado: (2013)

Type I Interferon Impairs Specific Antibody Responses Early during Establishment of LCMV Infection
por: Daugan, Matthieu, et al.
Publicado: (2016)

Understanding Experimental LCMV Infection of Mice: The Role of Mathematical Models
por: Bocharov, Gennady, et al.
Publicado: (2015)

T-cell STAT3 is required for the maintenance of humoral immunity to LCMV
por: McIlwain, David R, et al.
Publicado: (2015)

Crystal structure of the prefusion surface glycoprotein of the prototypic arenavirus LCMV
por: Hastie, Kathryn M., et al.
Publicado: (2016)

Complexities of Type I Interferon Biology: Lessons from LCMV
por: Suprunenko, Tamara, et al.
Publicado: (2019)

Human cases of lymphocytic choriomeningitis virus (LCMV) infections in Hungary
por: Pankovics, Péter, et al.
Publicado: (2023)

Interplay between regulatory T cells and PD-1 in modulating T cell exhaustion and viral control during chronic LCMV infection
por: Penaloza-MacMaster, Pablo, et al.
Publicado: (2014)

The transcription factors ZEB2 and T-bet cooperate to program cytotoxic T cell terminal differentiation in response to LCMV viral infection
por: Dominguez, Claudia X., et al.
Publicado: (2015)

Molecular analysis of the interaction of LCMV with its cellular receptor α-dystroglycan
por: Kunz, Stefan, et al.
Publicado: (2001)

T cells in the brain enhance neonatal mortality during peripheral LCMV infection
por: Kenney, Laurie L., et al.
Publicado: (2021)

Mast Cells Modulate Antigen-Specific CD8(+) T Cell Activation During LCMV Infection
por: Hackler, Yana, et al.
Publicado: (2021)

Large clones of pre-existing T cells drive early immunity against SARS-COV-2 and LCMV infection
por: Milighetti, Martina, et al.
Publicado: (2023)

Accelerated and Improved Quantification of Lymphocytic Choriomeningitis Virus (LCMV) Titers by Flow Cytometry
por: Korns Johnson, Darlynn, et al.
Publicado: (2012)

Source Activity Correlation Effects on LCMV Beamformers in a Realistic Measurement Environment
por: Belardinelli, Paolo, et al.
Publicado: (2012)

Heparan sulfate proteoglycans serve as alternative receptors for low affinity LCMV variants
por: Volland, André, et al.
Publicado: (2021)

LCMV induced downregulation of HVEM on antiviral T cells is critical for an efficient effector response
por: Diethelm, Patrizia, et al.
Publicado: (2022)

Development of Inflammatory Bowel Disease Is Linked to a Longitudinal Restructuring of the Gut Metagenome in Mice
por: Sharpton, Thomas, et al.
Publicado: (2017)

IRF4 and BATF are critical for CD8(+) T-cell function following infection with LCMV
por: Grusdat, M, et al.
Publicado: (2014)

IL-21 Restricts Virus-driven Treg Cell Expansion in Chronic LCMV Infection
por: Schmitz, Iwana, et al.
Publicado: (2013)

The lipid-sensor TREM2 aggravates disease in a model of LCMV-induced hepatitis
por: Kosack, Lindsay, et al.
Publicado: (2017)

Role of LFA-1 integrin in the control of a lymphocytic choriomeningitis virus (LCMV) infection
por: Perro, Mario, et al.
Publicado: (2020)

D471G Mutation in LCMV-NP Affects its Ability to Self-associate and Results in a Dominant Negative Effect in Viral RNA Synthesis
por: Ortiz-Riaño, Emilio, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_vfrumjdikbv7tqk4jpd97vle4h