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BROADLY NEUTRALIZING ANTIBODIES FROM HUMAN SURVIVORS TARGET A CONSERVED SITE IN THE EBOLA VIRUS GLYCOPROTEIN HR2/MPER REGION

Ebola virus (EBOV) in humans causes a severe illness with high mortality rates. Several strategies have been developed in the past to treat EBOV infection, including the antibody cocktail ZMapp(TM) that has been shown to be effective in nonhuman primate models of infection(1) and has been used under...

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Detalles Bibliográficos
Autores principales: Flyak, Andrew I., Kuzmina, Natalia, Murin, Charles D., Bryan, Christopher, Davidson, Edgar, Gilchuk, Pavlo, Gulka, Christopher P., Ilinykh, Philipp A., Shen, Xiaoli, Huang, Kai, Ramanathan, Palaniappan, Turner, Hannah, Fusco, Marnie L., Lampley, Rebecca, Kose, Nurgun, King, Hannah, Sapparapu, Gopal, Doranz, Benjamin J., Ksiazek, Thomas G., Wright, David W., Saphire, Erica Ollmann, Ward, Andrew B., Bukreyev, Alexander, Crowe, James E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030461/
https://www.ncbi.nlm.nih.gov/pubmed/29736037
http://dx.doi.org/10.1038/s41564-018-0157-z