The age of onset and evolution of Braak tangle stage and Thal amyloid pathology of Alzheimer’s disease in individuals with Down syndrome

While post mortem studies have identified the major cell types and functional systems affected in Alzheimer’s disease (AD) the initial sites and molecular characteristics of pathology are still unclear. Because individuals with Down syndrome (DS) (trisomy 21) develop the full pathological changes of...

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Detalles Bibliográficos
Autores principales: Davidson, Yvonne S., Robinson, Andrew, Prasher, Vee P., Mann, David M. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030772/
https://www.ncbi.nlm.nih.gov/pubmed/29973279
http://dx.doi.org/10.1186/s40478-018-0559-4

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