Reflection and observation: cell-based screening failing to detect HBV in HUMSCs derived from HBV-infected mothers underscores the importance of more stringent donor eligibility to reduce risk of transmission of infectious diseases for stem cell-based medical products

BACKGROUND: In cell-based therapy, the transmission of communicable diseases imposes a substantial threat to recipients. In this study, we investigated whether cell-based screening could detect hepatitis B virus (HBV) in human umbilical cord-derived mesenchymal stem cells (HUMSCs) isolated from HBV-...

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Detalles Bibliográficos
Autores principales: Liu, Wei, Xie, Yuanyuan, Gao, Tianyun, Huang, Feifei, Wang, Liudi, Ding, Lijun, Wang, Wenqing, Liu, Shuo, Dai, Jianwu, Wang, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030788/
https://www.ncbi.nlm.nih.gov/pubmed/29973264
http://dx.doi.org/10.1186/s13287-018-0920-3

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