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Sequential search leads to faster, more efficient fragment-based de novo protein structure prediction
MOTIVATION: Most current de novo structure prediction methods randomly sample protein conformations and thus require large amounts of computational resource. Here, we consider a sequential sampling strategy, building on ideas from recent experimental work which shows that many proteins fold cotransl...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030820/ https://www.ncbi.nlm.nih.gov/pubmed/29136098 http://dx.doi.org/10.1093/bioinformatics/btx722 |