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HotSpot Wizard 3.0: web server for automated design of mutations and smart libraries based on sequence input information
HotSpot Wizard is a web server used for the automated identification of hotspots in semi-rational protein design to give improved protein stability, catalytic activity, substrate specificity and enantioselectivity. Since there are three orders of magnitude fewer protein structures than sequences in...
Autores principales: | Sumbalova, Lenka, Stourac, Jan, Martinek, Tomas, Bednar, David, Damborsky, Jiri |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030891/ https://www.ncbi.nlm.nih.gov/pubmed/29796670 http://dx.doi.org/10.1093/nar/gky417 |
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