Novel nanocrystal-based solid dispersion with high drug loading, enhanced dissolution, and bioavailability of andrographolide

OBJECTIVE: The current study sought to design a quickly dissolving, high drug loading nanocrystal-based solid dispersion (NC-SD) in order to improve the dissolution of poorly soluble drugs. METHODS: The NC-SD was prepared by means of combination of homogenization and spray-drying. Polymer hydroxypro...

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Detalles Bibliográficos
Autores principales: Ma, Yueqin, Yang, Yang, Xie, Jin, Xu, Junnan, Yue, Pengfei, Yang, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030943/
https://www.ncbi.nlm.nih.gov/pubmed/29988798
http://dx.doi.org/10.2147/IJN.S164228

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030943/
https://www.ncbi.nlm.nih.gov/pubmed/29988798
http://dx.doi.org/10.2147/IJN.S164228

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