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Novel nanocrystal-based solid dispersion with high drug loading, enhanced dissolution, and bioavailability of andrographolide

OBJECTIVE: The current study sought to design a quickly dissolving, high drug loading nanocrystal-based solid dispersion (NC-SD) in order to improve the dissolution of poorly soluble drugs. METHODS: The NC-SD was prepared by means of combination of homogenization and spray-drying. Polymer hydroxypro...

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Detalles Bibliográficos
Autores principales:	Ma, Yueqin, Yang, Yang, Xie, Jin, Xu, Junnan, Yue, Pengfei, Yang, Ming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030943/ https://www.ncbi.nlm.nih.gov/pubmed/29988798 http://dx.doi.org/10.2147/IJN.S164228

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