Cargando…

Bringing numerous methods for expression and promoter analysis to a public cloud computing service

SUMMARY: Every year, a large number of novel algorithms are introduced to the scientific community for a myriad of applications, but using these across different research groups is often troublesome, due to suboptimal implementations and specific dependency requirements. This does not have to be the...

Descripción completa

Detalles Bibliográficos
Autores principales: Polański, Krzysztof, Gao, Bo, Mason, Sam A, Brown, Paul, Ott, Sascha, Denby, Katherine J, Wild, David L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030968/
https://www.ncbi.nlm.nih.gov/pubmed/29126246
http://dx.doi.org/10.1093/bioinformatics/btx692
_version_ 1783337229890879488
author Polański, Krzysztof
Gao, Bo
Mason, Sam A
Brown, Paul
Ott, Sascha
Denby, Katherine J
Wild, David L
author_facet Polański, Krzysztof
Gao, Bo
Mason, Sam A
Brown, Paul
Ott, Sascha
Denby, Katherine J
Wild, David L
author_sort Polański, Krzysztof
collection PubMed
description SUMMARY: Every year, a large number of novel algorithms are introduced to the scientific community for a myriad of applications, but using these across different research groups is often troublesome, due to suboptimal implementations and specific dependency requirements. This does not have to be the case, as public cloud computing services can easily house tractable implementations within self-contained dependency environments, making the methods easily accessible to a wider public. We have taken 14 popular methods, the majority related to expression data or promoter analysis, developed these up to a good implementation standard and housed the tools in isolated Docker containers which we integrated into the CyVerse Discovery Environment, making these easily usable for a wide community as part of the CyVerse UK project. AVAILABILITY AND IMPLEMENTATION: The integrated apps can be found at http://www.cyverse.org/discovery-environment, while the raw code is available at https://github.com/cyversewarwick and the corresponding Docker images are housed at https://hub.docker.com/r/cyversewarwick/. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.
format Online
Article
Text
id pubmed-6030968
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Oxford University Press
record_format MEDLINE/PubMed
spelling pubmed-60309682018-07-10 Bringing numerous methods for expression and promoter analysis to a public cloud computing service Polański, Krzysztof Gao, Bo Mason, Sam A Brown, Paul Ott, Sascha Denby, Katherine J Wild, David L Bioinformatics Applications Notes SUMMARY: Every year, a large number of novel algorithms are introduced to the scientific community for a myriad of applications, but using these across different research groups is often troublesome, due to suboptimal implementations and specific dependency requirements. This does not have to be the case, as public cloud computing services can easily house tractable implementations within self-contained dependency environments, making the methods easily accessible to a wider public. We have taken 14 popular methods, the majority related to expression data or promoter analysis, developed these up to a good implementation standard and housed the tools in isolated Docker containers which we integrated into the CyVerse Discovery Environment, making these easily usable for a wide community as part of the CyVerse UK project. AVAILABILITY AND IMPLEMENTATION: The integrated apps can be found at http://www.cyverse.org/discovery-environment, while the raw code is available at https://github.com/cyversewarwick and the corresponding Docker images are housed at https://hub.docker.com/r/cyversewarwick/. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online. Oxford University Press 2018-03-01 2017-11-06 /pmc/articles/PMC6030968/ /pubmed/29126246 http://dx.doi.org/10.1093/bioinformatics/btx692 Text en © The Author 2017. Published by Oxford University Press. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Applications Notes
Polański, Krzysztof
Gao, Bo
Mason, Sam A
Brown, Paul
Ott, Sascha
Denby, Katherine J
Wild, David L
Bringing numerous methods for expression and promoter analysis to a public cloud computing service
title Bringing numerous methods for expression and promoter analysis to a public cloud computing service
title_full Bringing numerous methods for expression and promoter analysis to a public cloud computing service
title_fullStr Bringing numerous methods for expression and promoter analysis to a public cloud computing service
title_full_unstemmed Bringing numerous methods for expression and promoter analysis to a public cloud computing service
title_short Bringing numerous methods for expression and promoter analysis to a public cloud computing service
title_sort bringing numerous methods for expression and promoter analysis to a public cloud computing service
topic Applications Notes
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030968/
https://www.ncbi.nlm.nih.gov/pubmed/29126246
http://dx.doi.org/10.1093/bioinformatics/btx692
work_keys_str_mv AT polanskikrzysztof bringingnumerousmethodsforexpressionandpromoteranalysistoapubliccloudcomputingservice
AT gaobo bringingnumerousmethodsforexpressionandpromoteranalysistoapubliccloudcomputingservice
AT masonsama bringingnumerousmethodsforexpressionandpromoteranalysistoapubliccloudcomputingservice
AT brownpaul bringingnumerousmethodsforexpressionandpromoteranalysistoapubliccloudcomputingservice
AT ottsascha bringingnumerousmethodsforexpressionandpromoteranalysistoapubliccloudcomputingservice
AT denbykatherinej bringingnumerousmethodsforexpressionandpromoteranalysistoapubliccloudcomputingservice
AT wilddavidl bringingnumerousmethodsforexpressionandpromoteranalysistoapubliccloudcomputingservice