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The transformics assay: first steps for the development of an integrated approach to investigate the malignant cell transformation in vitro
The development of alternative methods to animal testing is a priority in the context of regulatory toxicology. Carcinogenesis is a field where the demand for alternative methods is particularly high. The standard rodent carcinogenicity bioassay requires a large use of animals, high costs, prolonged...
Autores principales: | Mascolo, Maria Grazia, Perdichizzi, Stefania, Vaccari, Monica, Rotondo, Francesca, Zanzi, Cristina, Grilli, Sandro, Paparella, Martin, Jacobs, Miriam N, Colacci, Annamaria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031005/ https://www.ncbi.nlm.nih.gov/pubmed/29554273 http://dx.doi.org/10.1093/carcin/bgy037 |
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