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AFF4 promotes tumorigenesis and tumor-initiation capacity of head and neck squamous cell carcinoma cells by regulating SOX2

Super elongation complex (SEC) controls gene transcription by releasing Pol II from pausing. Previous studies have shown that dysfunction of SEC was associated with multiple human cancers, such as leukemia and breast cancer. However, the role of SEC in head and neck squamous cell carcinoma (HNSCC) d...

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Detalles Bibliográficos
Autores principales:	Deng, Peng, Wang, Jiongke, Zhang, Xuefeng, Wu, Xingyu, Ji, Ning, Li, Jing, Zhou, Min, Jiang, Lu, Zeng, Xin, Chen, Qianming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2018
Materias:	Carcinogenesis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031063/ https://www.ncbi.nlm.nih.gov/pubmed/29741610 http://dx.doi.org/10.1093/carcin/bgy046

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