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Aberrant Promoter Methylation of YAP Gene and its Subsequent Downregulation in Indian Breast Cancer Patients

BACKGROUND: YAP, a potent oncogene and major downstream effector of the mammalian Hippo tumor suppressor pathway can act as either oncogene or tumor suppressor gene based on the type of tissue involved. Despite various studies, the role and mechanism through which YAP mediates its tumor suppressor o...

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Detalles Bibliográficos
Autores principales:	Real, Sumayya Abdul Sattar, Parveen, Farah, Rehman, Asad Ur, Khan, Mohammad Aasif, Deo, Sankaravamasam Venkata Suryanarayan, Shukla, Nootan Kumar, Husain, Syed Akhtar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031145/ https://www.ncbi.nlm.nih.gov/pubmed/29970036 http://dx.doi.org/10.1186/s12885-018-4627-8

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