Completion of genome of Aeromonas salmonicida subsp. salmonicida 01-B526 reveals how sequencing technologies can influence sequence quality and result interpretations

Aeromonas salmonicida subsp. salmonicida is a pathogen that primarily infects salmonids. A strain of this bacterium, 01-B526, has been used in several studies as a reference. The genomic sequence of this strain is available, but comes from pyrosequencing and is the second most fragmented assembly fo...

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Detalles Bibliográficos
Autores principales: Vincent, A.T., Charette, S.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Taxonogenomics: Genome of a Known Organism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031243/
https://www.ncbi.nlm.nih.gov/pubmed/29983988
http://dx.doi.org/10.1016/j.nmni.2018.05.007
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author Vincent, A.T.
Charette, S.J.
author_facet Vincent, A.T.
Charette, S.J.
author_sort Vincent, A.T.
collection PubMed
description Aeromonas salmonicida subsp. salmonicida is a pathogen that primarily infects salmonids. A strain of this bacterium, 01-B526, has been used in several studies as a reference. The genomic sequence of this strain is available, but comes from pyrosequencing and is the second most fragmented assembly for this bacterium. We generated its closed genome sequence and found a pitfall in result interpretations associated with low-quality genomic sequences.
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spelling pubmed-60312432018-07-06 Completion of genome of Aeromonas salmonicida subsp. salmonicida 01-B526 reveals how sequencing technologies can influence sequence quality and result interpretations Vincent, A.T. Charette, S.J. New Microbes New Infect Taxonogenomics: Genome of a Known Organism Aeromonas salmonicida subsp. salmonicida is a pathogen that primarily infects salmonids. A strain of this bacterium, 01-B526, has been used in several studies as a reference. The genomic sequence of this strain is available, but comes from pyrosequencing and is the second most fragmented assembly for this bacterium. We generated its closed genome sequence and found a pitfall in result interpretations associated with low-quality genomic sequences. Elsevier 2018-05-31 /pmc/articles/PMC6031243/ /pubmed/29983988 http://dx.doi.org/10.1016/j.nmni.2018.05.007 Text en © 2018 The Author(s) http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Taxonogenomics: Genome of a Known Organism
Vincent, A.T.
Charette, S.J.
Completion of genome of Aeromonas salmonicida subsp. salmonicida 01-B526 reveals how sequencing technologies can influence sequence quality and result interpretations
title Completion of genome of Aeromonas salmonicida subsp. salmonicida 01-B526 reveals how sequencing technologies can influence sequence quality and result interpretations
title_full Completion of genome of Aeromonas salmonicida subsp. salmonicida 01-B526 reveals how sequencing technologies can influence sequence quality and result interpretations
title_fullStr Completion of genome of Aeromonas salmonicida subsp. salmonicida 01-B526 reveals how sequencing technologies can influence sequence quality and result interpretations
title_full_unstemmed Completion of genome of Aeromonas salmonicida subsp. salmonicida 01-B526 reveals how sequencing technologies can influence sequence quality and result interpretations
title_short Completion of genome of Aeromonas salmonicida subsp. salmonicida 01-B526 reveals how sequencing technologies can influence sequence quality and result interpretations
title_sort completion of genome of aeromonas salmonicida subsp. salmonicida 01-b526 reveals how sequencing technologies can influence sequence quality and result interpretations
topic Taxonogenomics: Genome of a Known Organism
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031243/
https://www.ncbi.nlm.nih.gov/pubmed/29983988
http://dx.doi.org/10.1016/j.nmni.2018.05.007
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