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Nmnat mitigates sensory dysfunction in a Drosophila model of paclitaxel-induced peripheral neuropathy

Chemotherapy-induced peripheral neuropathy (CIPN) is the major dose-limiting side effect of many commonly used chemotherapeutic agents, including paclitaxel. Currently, there are no neuroprotective or effective symptomatic treatments for CIPN. Lack of understanding of the in vivo mechanisms of CIPN...

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Detalles Bibliográficos
Autores principales: Brazill, Jennifer M., Cruz, Beverley, Zhu, Yi, Zhai, R. Grace
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031360/
https://www.ncbi.nlm.nih.gov/pubmed/29716954
http://dx.doi.org/10.1242/dmm.032938

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