Adding a temporal dimension to the study of Friedreich's ataxia: the effect of frataxin overexpression in a human cell model

The neurodegenerative disease Friedreich's ataxia is caused by lower than normal levels of frataxin, an important protein involved in iron–sulfur (Fe-S) cluster biogenesis. An important step in designing strategies to treat this disease is to understand whether increasing the frataxin levels by...

Descripción completa

Detalles Bibliográficos
Autores principales: Vannocci, Tommaso, Notario Manzano, Roberto, Beccalli, Ombretta, Bettegazzi, Barbara, Grohovaz, Fabio, Cinque, Gianfelice, de Riso, Antonio, Quaroni, Luca, Codazzi, Franca, Pastore, Annalisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031361/
https://www.ncbi.nlm.nih.gov/pubmed/29794127
http://dx.doi.org/10.1242/dmm.032706

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031361/
https://www.ncbi.nlm.nih.gov/pubmed/29794127
http://dx.doi.org/10.1242/dmm.032706

Ejemplares similares