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Oct4 regulates the embryonic axis and coordinates exit from pluripotency and germ layer specification in the mouse embryo
Lineage segregation in the mouse embryo is a finely controlled process dependent upon coordination of signalling pathways and transcriptional responses. Here we employ a conditional deletion system to investigate embryonic patterning and lineage specification in response to loss of Oct4. We first ob...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Company of Biologists Ltd
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031404/ https://www.ncbi.nlm.nih.gov/pubmed/29915126 http://dx.doi.org/10.1242/dev.159103 |