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Cell size sensing in animal cells coordinates anabolic growth rates and cell cycle progression to maintain cell size uniformity

Cell size uniformity in healthy tissues suggests that control mechanisms might coordinate cell growth and division. We derived a method to assay whether cellular growth rates depend on cell size, by monitoring how variance in size changes as cells grow. Our data revealed that, twice during the cell...

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Detalles Bibliográficos
Autores principales: Ginzberg, Miriam Bracha, Chang, Nancy, D'Souza, Heather, Patel, Nish, Kafri, Ran, Kirschner, Marc W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031432/
https://www.ncbi.nlm.nih.gov/pubmed/29889021
http://dx.doi.org/10.7554/eLife.26957