Cargando…
Cell size sensing in animal cells coordinates anabolic growth rates and cell cycle progression to maintain cell size uniformity
Cell size uniformity in healthy tissues suggests that control mechanisms might coordinate cell growth and division. We derived a method to assay whether cellular growth rates depend on cell size, by monitoring how variance in size changes as cells grow. Our data revealed that, twice during the cell...
Autores principales: | Ginzberg, Miriam Bracha, Chang, Nancy, D'Souza, Heather, Patel, Nish, Kafri, Ran, Kirschner, Marc W |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031432/ https://www.ncbi.nlm.nih.gov/pubmed/29889021 http://dx.doi.org/10.7554/eLife.26957 |
Ejemplares similares
-
Size uniformity of animal cells is actively maintained by a p38 MAPK-dependent regulation of G1-length
por: Liu, Shixuan, et al.
Publicado: (2018) -
What programs the size of animal cells?
por: Liu, Shixuan, et al.
Publicado: (2022) -
YAP regulates cell size and growth dynamics via non-cell autonomous mediators
por: Mugahid, Douaa, et al.
Publicado: (2020) -
The uniformity and stability of cellular mass density in mammalian cell culture
por: Liu, Xili, et al.
Publicado: (2022) -
Is cell size a spandrel?
por: Amir, Ariel
Publicado: (2017)