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Concurrent TSHR mutations and DIO2 T92A polymorphism result in abnormal thyroid hormone metabolism

Deiodinase 2 (DIO2) plays an important role in thyroid hormone metabolism and its regulation. However, molecular mechanism that regulates DIO2 activity remains unclear; only mutaions in selenocysteine insertion sequence binding protein 2 and selenocysteine tranfer RNA (tRNA([Ser]Sec)) are reported t...

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Detalles Bibliográficos
Autores principales:	Park, Eunkuk, Jung, Jaehoon, Araki, Osamu, Tsunekawa, Katsuhiko, Park, So Young, Kim, Jeonghyun, Murakami, Masami, Jeong, Seon-Yong, Lee, Sihoon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031622/ https://www.ncbi.nlm.nih.gov/pubmed/29973617 http://dx.doi.org/10.1038/s41598-018-28480-0

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