XPC is an RNA polymerase II cofactor recruiting ATAC to promoters by interacting with E2F1

The DNA damage sensor XPC is involved in nucleotide excision repair. Here we show that in the absence of damage, XPC co-localizes with RNA polymerase II (Pol II) and active post-translational histone modifications marks on a subset of class II promoters in human fibroblasts. XPC depletion triggers s...

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Detalles Bibliográficos
Autores principales: Bidon, B., Iltis, I., Semer, M., Nagy, Z., Larnicol, A., Cribier, A., Benkirane, M., Coin, F., Egly, J-M., Le May, N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031651/
https://www.ncbi.nlm.nih.gov/pubmed/29973595
http://dx.doi.org/10.1038/s41467-018-05010-0

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