MicroRNA interactome analysis predicts post-transcriptional regulation of ADRB2 and PPP3R1 in the hypercholesterolemic myocardium

Little is known about the molecular mechanism including microRNAs (miRNA) in hypercholesterolemia-induced cardiac dysfunction. We aimed to explore novel hypercholesterolemia-induced pathway alterations in the heart by an unbiased approach based on miRNA omics, target prediction and validation. With...

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Detalles Bibliográficos
Autores principales: Ágg, Bence, Baranyai, Tamás, Makkos, András, Vető, Borbála, Faragó, Nóra, Zvara, Ágnes, Giricz, Zoltán, Veres, Dániel V., Csermely, Péter, Arányi, Tamás, Puskás, László G., Varga, Zoltán V., Ferdinandy, Péter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031673/
https://www.ncbi.nlm.nih.gov/pubmed/29973623
http://dx.doi.org/10.1038/s41598-018-27740-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031673/
https://www.ncbi.nlm.nih.gov/pubmed/29973623
http://dx.doi.org/10.1038/s41598-018-27740-3

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