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MicroRNA interactome analysis predicts post-transcriptional regulation of ADRB2 and PPP3R1 in the hypercholesterolemic myocardium
Little is known about the molecular mechanism including microRNAs (miRNA) in hypercholesterolemia-induced cardiac dysfunction. We aimed to explore novel hypercholesterolemia-induced pathway alterations in the heart by an unbiased approach based on miRNA omics, target prediction and validation. With...
Autores principales: | Ágg, Bence, Baranyai, Tamás, Makkos, András, Vető, Borbála, Faragó, Nóra, Zvara, Ágnes, Giricz, Zoltán, Veres, Dániel V., Csermely, Péter, Arányi, Tamás, Puskás, László G., Varga, Zoltán V., Ferdinandy, Péter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031673/ https://www.ncbi.nlm.nih.gov/pubmed/29973623 http://dx.doi.org/10.1038/s41598-018-27740-3 |
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