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Dosage compensation and DNA methylation landscape of the X chromosome in mouse liver

DNA methylation plays a key role in X-chromosome inactivation (XCI), a process that achieves dosage compensation for X-encoded gene products between mammalian female and male cells. However, differential sex chromosome dosage complicates genome-wide epigenomic assessments, and the X chromosome is fr...

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Detalles Bibliográficos
Autores principales:	Duncan, Christopher G., Grimm, Sara A., Morgan, Daniel L., Bushel, Pierre R., Bennett, Brian D., Roberts, John D., Tyson, Frederick L., Merrick, B. Alex, Wade, Paul A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031675/ https://www.ncbi.nlm.nih.gov/pubmed/29973619 http://dx.doi.org/10.1038/s41598-018-28356-3

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