Rapid transport of deformation-tuned nanoparticles across biological hydrogels and cellular barriers

To optimally penetrate biological hydrogels such as mucus and the tumor interstitial matrix, nanoparticles (NPs) require physicochemical properties that would typically preclude cellular uptake, resulting in inefficient drug delivery. Here, we demonstrate that (poly(lactic-co-glycolic acid) (PLGA) c...

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Detalles Bibliográficos
Autores principales: Yu, Miaorong, Xu, Lu, Tian, Falin, Su, Qian, Zheng, Nan, Yang, Yiwei, Wang, Jiuling, Wang, Aohua, Zhu, Chunliu, Guo, Shiyan, Zhang, XinXin, Gan, Yong, Shi, Xinghua, Gao, Huajian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031689/
https://www.ncbi.nlm.nih.gov/pubmed/29973592
http://dx.doi.org/10.1038/s41467-018-05061-3

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