The Orexin/Receptor System: Molecular Mechanism and Therapeutic Potential for Neurological Diseases

Orexins, also known as hypocretins, are two neuropeptides secreted from orexin-containing neurons, mainly in the lateral hypothalamus (LH). Orexins orchestrate their effects by binding and activating two G-protein–coupled receptors (GPCRs), orexin receptor type 1 (OX1R) and type 2 (OX2R). Orexin/rec...

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Detalles Bibliográficos
Autores principales: Wang, Chunmei, Wang, Qinqin, Ji, Bingyuan, Pan, Yanyou, Xu, Chao, Cheng, Baohua, Bai, Bo, Chen, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031739/
https://www.ncbi.nlm.nih.gov/pubmed/30002617
http://dx.doi.org/10.3389/fnmol.2018.00220

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031739/
https://www.ncbi.nlm.nih.gov/pubmed/30002617
http://dx.doi.org/10.3389/fnmol.2018.00220

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