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Front Cover: Synthesis and Characterization of Novel Fluoro‐glycosylated Porphyrins that can be Utilized as Theranostic Agents (ChemistryOpen 7/2018)
The Front Cover shows a fluoro‐glycoporphyrin that selectively targets cancer cells. The selectivity towards cancer cells are afforded due to proper functionalization of the porphyrin scaffold with specific carbohydrates, and the cancer cells can be visualized because of the intrinsic fluorescence f...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031854/ http://dx.doi.org/10.1002/open.201800096 |
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author | Arja, Katriann Elgland, Mathias Appelqvist, Hanna Konradsson, Peter Lindgren, Mikael Nilsson, K. Peter R. |
author_facet | Arja, Katriann Elgland, Mathias Appelqvist, Hanna Konradsson, Peter Lindgren, Mikael Nilsson, K. Peter R. |
author_sort | Arja, Katriann |
collection | PubMed |
description | The Front Cover shows a fluoro‐glycoporphyrin that selectively targets cancer cells. The selectivity towards cancer cells are afforded due to proper functionalization of the porphyrin scaffold with specific carbohydrates, and the cancer cells can be visualized because of the intrinsic fluorescence from the porphyrin. The molecule also exhibits properties for photodynamic therapy and the incorporation of fluorine, in the form of 2‐fluoro‐2‐deoxy glucose, offers the possibility to apply these compounds as 18F positron emission tomography tracers. Thus, fluoro‐glycoporphyrins display multimodal properties and can be employed as theranostic agents targeting cancer cells. More information can be found in the Full Paper by K. P. R. Nilsson and co‐workers on page 495 in Issue 7, 2018 (DOI: https://doi.org/10.1002/open.201800020).[Image: see text] |
format | Online Article Text |
id | pubmed-6031854 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-60318542018-07-12 Front Cover: Synthesis and Characterization of Novel Fluoro‐glycosylated Porphyrins that can be Utilized as Theranostic Agents (ChemistryOpen 7/2018) Arja, Katriann Elgland, Mathias Appelqvist, Hanna Konradsson, Peter Lindgren, Mikael Nilsson, K. Peter R. ChemistryOpen Cover Pictures The Front Cover shows a fluoro‐glycoporphyrin that selectively targets cancer cells. The selectivity towards cancer cells are afforded due to proper functionalization of the porphyrin scaffold with specific carbohydrates, and the cancer cells can be visualized because of the intrinsic fluorescence from the porphyrin. The molecule also exhibits properties for photodynamic therapy and the incorporation of fluorine, in the form of 2‐fluoro‐2‐deoxy glucose, offers the possibility to apply these compounds as 18F positron emission tomography tracers. Thus, fluoro‐glycoporphyrins display multimodal properties and can be employed as theranostic agents targeting cancer cells. More information can be found in the Full Paper by K. P. R. Nilsson and co‐workers on page 495 in Issue 7, 2018 (DOI: https://doi.org/10.1002/open.201800020).[Image: see text] John Wiley and Sons Inc. 2018-06-01 /pmc/articles/PMC6031854/ http://dx.doi.org/10.1002/open.201800096 Text en © 2018 Wiley‐VCH Verlag GmbH & Co. KGaA, Weinheim |
spellingShingle | Cover Pictures Arja, Katriann Elgland, Mathias Appelqvist, Hanna Konradsson, Peter Lindgren, Mikael Nilsson, K. Peter R. Front Cover: Synthesis and Characterization of Novel Fluoro‐glycosylated Porphyrins that can be Utilized as Theranostic Agents (ChemistryOpen 7/2018) |
title | Front Cover: Synthesis and Characterization of Novel Fluoro‐glycosylated Porphyrins that can be Utilized as Theranostic Agents (ChemistryOpen 7/2018) |
title_full | Front Cover: Synthesis and Characterization of Novel Fluoro‐glycosylated Porphyrins that can be Utilized as Theranostic Agents (ChemistryOpen 7/2018) |
title_fullStr | Front Cover: Synthesis and Characterization of Novel Fluoro‐glycosylated Porphyrins that can be Utilized as Theranostic Agents (ChemistryOpen 7/2018) |
title_full_unstemmed | Front Cover: Synthesis and Characterization of Novel Fluoro‐glycosylated Porphyrins that can be Utilized as Theranostic Agents (ChemistryOpen 7/2018) |
title_short | Front Cover: Synthesis and Characterization of Novel Fluoro‐glycosylated Porphyrins that can be Utilized as Theranostic Agents (ChemistryOpen 7/2018) |
title_sort | front cover: synthesis and characterization of novel fluoro‐glycosylated porphyrins that can be utilized as theranostic agents (chemistryopen 7/2018) |
topic | Cover Pictures |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031854/ http://dx.doi.org/10.1002/open.201800096 |
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