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Front Cover: Synthesis and Characterization of Novel Fluoro‐glycosylated Porphyrins that can be Utilized as Theranostic Agents (ChemistryOpen 7/2018)

The Front Cover shows a fluoro‐glycoporphyrin that selectively targets cancer cells. The selectivity towards cancer cells are afforded due to proper functionalization of the porphyrin scaffold with specific carbohydrates, and the cancer cells can be visualized because of the intrinsic fluorescence f...

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Detalles Bibliográficos
Autores principales: Arja, Katriann, Elgland, Mathias, Appelqvist, Hanna, Konradsson, Peter, Lindgren, Mikael, Nilsson, K. Peter R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031854/
http://dx.doi.org/10.1002/open.201800096
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author Arja, Katriann
Elgland, Mathias
Appelqvist, Hanna
Konradsson, Peter
Lindgren, Mikael
Nilsson, K. Peter R.
author_facet Arja, Katriann
Elgland, Mathias
Appelqvist, Hanna
Konradsson, Peter
Lindgren, Mikael
Nilsson, K. Peter R.
author_sort Arja, Katriann
collection PubMed
description The Front Cover shows a fluoro‐glycoporphyrin that selectively targets cancer cells. The selectivity towards cancer cells are afforded due to proper functionalization of the porphyrin scaffold with specific carbohydrates, and the cancer cells can be visualized because of the intrinsic fluorescence from the porphyrin. The molecule also exhibits properties for photodynamic therapy and the incorporation of fluorine, in the form of 2‐fluoro‐2‐deoxy glucose, offers the possibility to apply these compounds as 18F positron emission tomography tracers. Thus, fluoro‐glycoporphyrins display multimodal properties and can be employed as theranostic agents targeting cancer cells. More information can be found in the Full Paper by K. P. R. Nilsson and co‐workers on page 495 in Issue 7, 2018 (DOI: https://doi.org/10.1002/open.201800020).[Image: see text]
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spelling pubmed-60318542018-07-12 Front Cover: Synthesis and Characterization of Novel Fluoro‐glycosylated Porphyrins that can be Utilized as Theranostic Agents (ChemistryOpen 7/2018) Arja, Katriann Elgland, Mathias Appelqvist, Hanna Konradsson, Peter Lindgren, Mikael Nilsson, K. Peter R. ChemistryOpen Cover Pictures The Front Cover shows a fluoro‐glycoporphyrin that selectively targets cancer cells. The selectivity towards cancer cells are afforded due to proper functionalization of the porphyrin scaffold with specific carbohydrates, and the cancer cells can be visualized because of the intrinsic fluorescence from the porphyrin. The molecule also exhibits properties for photodynamic therapy and the incorporation of fluorine, in the form of 2‐fluoro‐2‐deoxy glucose, offers the possibility to apply these compounds as 18F positron emission tomography tracers. Thus, fluoro‐glycoporphyrins display multimodal properties and can be employed as theranostic agents targeting cancer cells. More information can be found in the Full Paper by K. P. R. Nilsson and co‐workers on page 495 in Issue 7, 2018 (DOI: https://doi.org/10.1002/open.201800020).[Image: see text] John Wiley and Sons Inc. 2018-06-01 /pmc/articles/PMC6031854/ http://dx.doi.org/10.1002/open.201800096 Text en © 2018 Wiley‐VCH Verlag GmbH & Co. KGaA, Weinheim
spellingShingle Cover Pictures
Arja, Katriann
Elgland, Mathias
Appelqvist, Hanna
Konradsson, Peter
Lindgren, Mikael
Nilsson, K. Peter R.
Front Cover: Synthesis and Characterization of Novel Fluoro‐glycosylated Porphyrins that can be Utilized as Theranostic Agents (ChemistryOpen 7/2018)
title Front Cover: Synthesis and Characterization of Novel Fluoro‐glycosylated Porphyrins that can be Utilized as Theranostic Agents (ChemistryOpen 7/2018)
title_full Front Cover: Synthesis and Characterization of Novel Fluoro‐glycosylated Porphyrins that can be Utilized as Theranostic Agents (ChemistryOpen 7/2018)
title_fullStr Front Cover: Synthesis and Characterization of Novel Fluoro‐glycosylated Porphyrins that can be Utilized as Theranostic Agents (ChemistryOpen 7/2018)
title_full_unstemmed Front Cover: Synthesis and Characterization of Novel Fluoro‐glycosylated Porphyrins that can be Utilized as Theranostic Agents (ChemistryOpen 7/2018)
title_short Front Cover: Synthesis and Characterization of Novel Fluoro‐glycosylated Porphyrins that can be Utilized as Theranostic Agents (ChemistryOpen 7/2018)
title_sort front cover: synthesis and characterization of novel fluoro‐glycosylated porphyrins that can be utilized as theranostic agents (chemistryopen 7/2018)
topic Cover Pictures
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031854/
http://dx.doi.org/10.1002/open.201800096
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