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Hand Tremor Questionnaire: A Useful Screening Tool for Differentiating Patients with Hand Tremor between Parkinson's Disease and Essential Tremor

BACKGROUND AND PURPOSE: Hand tremor is one of the most frequent symptoms in movement disorders, and differential diagnoses for hand tremor include Parkinson's disease (PD) and essential tremor (ET). However, accurately differentiating between PD and ET in clinical practice remains challenging i...

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Autores principales: Kwon, Kyum-Yil, Ryu, Ho-Sung, Lee, Hye Mi, Kim, Mi-Jung, Shin, Hae-Won, Park, Hee Kyung, You, Sooyeoun, Sung, Young-Hee, Chung, Sun Ju, Koh, Seong-Beom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Neurological Association 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031988/
https://www.ncbi.nlm.nih.gov/pubmed/29971978
http://dx.doi.org/10.3988/jcn.2018.14.3.381
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author Kwon, Kyum-Yil
Ryu, Ho-Sung
Lee, Hye Mi
Kim, Mi-Jung
Shin, Hae-Won
Park, Hee Kyung
You, Sooyeoun
Sung, Young-Hee
Chung, Sun Ju
Koh, Seong-Beom
author_facet Kwon, Kyum-Yil
Ryu, Ho-Sung
Lee, Hye Mi
Kim, Mi-Jung
Shin, Hae-Won
Park, Hee Kyung
You, Sooyeoun
Sung, Young-Hee
Chung, Sun Ju
Koh, Seong-Beom
author_sort Kwon, Kyum-Yil
collection PubMed
description BACKGROUND AND PURPOSE: Hand tremor is one of the most frequent symptoms in movement disorders, and differential diagnoses for hand tremor include Parkinson's disease (PD) and essential tremor (ET). However, accurately differentiating between PD and ET in clinical practice remains challenging in patients presenting with hand tremor. We investigated whether a questionnaire-based survey could be useful as a screening tool in patients with hand tremor. METHODS: A questionnaire related to hand tremor consisting of 12 items was prospectively applied to patients with PD or ET in three movement-disorder clinics. Each question was analyzed, and a query-based scoring system was evaluated for differentiating hand tremors between PD and ET. RESULTS: This study enrolled 24 patients with PD and 25 patients with ET. Nine of the 12 questions differed significantly between PD and ET: 1 about resting tremor, 4 questions about action tremor, and 4 about asymmetry. A receiver operating characteristics curve analysis revealed that the 9-item questionnaire showed a good discrimination ability, with a sensitivity of 88% and a specificity of 84%. CONCLUSIONS: The developed Hand Tremor Questionnaire might be a good screening tool for hand tremors in patients with PD and ET.
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spelling pubmed-60319882018-07-06 Hand Tremor Questionnaire: A Useful Screening Tool for Differentiating Patients with Hand Tremor between Parkinson's Disease and Essential Tremor Kwon, Kyum-Yil Ryu, Ho-Sung Lee, Hye Mi Kim, Mi-Jung Shin, Hae-Won Park, Hee Kyung You, Sooyeoun Sung, Young-Hee Chung, Sun Ju Koh, Seong-Beom J Clin Neurol Original Article BACKGROUND AND PURPOSE: Hand tremor is one of the most frequent symptoms in movement disorders, and differential diagnoses for hand tremor include Parkinson's disease (PD) and essential tremor (ET). However, accurately differentiating between PD and ET in clinical practice remains challenging in patients presenting with hand tremor. We investigated whether a questionnaire-based survey could be useful as a screening tool in patients with hand tremor. METHODS: A questionnaire related to hand tremor consisting of 12 items was prospectively applied to patients with PD or ET in three movement-disorder clinics. Each question was analyzed, and a query-based scoring system was evaluated for differentiating hand tremors between PD and ET. RESULTS: This study enrolled 24 patients with PD and 25 patients with ET. Nine of the 12 questions differed significantly between PD and ET: 1 about resting tremor, 4 questions about action tremor, and 4 about asymmetry. A receiver operating characteristics curve analysis revealed that the 9-item questionnaire showed a good discrimination ability, with a sensitivity of 88% and a specificity of 84%. CONCLUSIONS: The developed Hand Tremor Questionnaire might be a good screening tool for hand tremors in patients with PD and ET. Korean Neurological Association 2018-07 2018-06-29 /pmc/articles/PMC6031988/ /pubmed/29971978 http://dx.doi.org/10.3988/jcn.2018.14.3.381 Text en Copyright © 2018 Korean Neurological Association http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Kwon, Kyum-Yil
Ryu, Ho-Sung
Lee, Hye Mi
Kim, Mi-Jung
Shin, Hae-Won
Park, Hee Kyung
You, Sooyeoun
Sung, Young-Hee
Chung, Sun Ju
Koh, Seong-Beom
Hand Tremor Questionnaire: A Useful Screening Tool for Differentiating Patients with Hand Tremor between Parkinson's Disease and Essential Tremor
title Hand Tremor Questionnaire: A Useful Screening Tool for Differentiating Patients with Hand Tremor between Parkinson's Disease and Essential Tremor
title_full Hand Tremor Questionnaire: A Useful Screening Tool for Differentiating Patients with Hand Tremor between Parkinson's Disease and Essential Tremor
title_fullStr Hand Tremor Questionnaire: A Useful Screening Tool for Differentiating Patients with Hand Tremor between Parkinson's Disease and Essential Tremor
title_full_unstemmed Hand Tremor Questionnaire: A Useful Screening Tool for Differentiating Patients with Hand Tremor between Parkinson's Disease and Essential Tremor
title_short Hand Tremor Questionnaire: A Useful Screening Tool for Differentiating Patients with Hand Tremor between Parkinson's Disease and Essential Tremor
title_sort hand tremor questionnaire: a useful screening tool for differentiating patients with hand tremor between parkinson's disease and essential tremor
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031988/
https://www.ncbi.nlm.nih.gov/pubmed/29971978
http://dx.doi.org/10.3988/jcn.2018.14.3.381
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