STIM1 Knockout Enhances PDGF-Mediated Ca(2+) Signaling through Upregulation of the PDGFR–PLCγ–STIM2 Cascade

Platelet-derived growth factor (PDGF) has mitogenic and chemotactic effects on fibroblasts. An increase in intracellular Ca(2+) is one of the first events that occurs following the stimulation of PDGF receptors (PDGFRs). PDGF activates Ca(2+) elevation by activating the phospholipase C gamma (PLCγ)-...

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Detalles Bibliográficos
Autores principales: Huang, Tzu-Yu, Lin, Yi-Hsin, Chang, Heng-Ai, Yeh, Tzu-Ying, Chang, Ya-Han, Chen, Yi-Fan, Chen, Ying-Chi, Li, Chun-Chun, Chiu, Wen-Tai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032054/
https://www.ncbi.nlm.nih.gov/pubmed/29912163
http://dx.doi.org/10.3390/ijms19061799

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