Structure–Activity Relationship of Piplartine and Synthetic Analogues against Schistosoma mansoni and Cytotoxicity to Mammalian Cells

Schistosomiasis, caused by helminth flatworms of the genus Schistosoma, is an infectious disease mainly associated with poverty that affects millions of people worldwide. Since treatment for this disease relies only on the use of praziquantel, there is an urgent need to identify new antischistosomal...

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Detalles Bibliográficos
Autores principales: Campelo, Yuri, Ombredane, Alicia, Vasconcelos, Andreanne G., Albuquerque, Lucas, Moreira, Daniel C., Plácido, Alexandra, Rocha, Jefferson, Hilarion Fokoue, Harold, Yamaguchi, Lydia, Mafud, Ana, Mascarenhas, Yvonne P., Delerue-Matos, Cristina, Borges, Tatiana, Joanitti, Graziella A., Arcanjo, D. R. Daniel, Kato, Massuo J., Kuckelhaus, Selma A. S., Silva, Marcos P. N., de Moraes, Josué, Leite, José Roberto S. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032158/
https://www.ncbi.nlm.nih.gov/pubmed/29921756
http://dx.doi.org/10.3390/ijms19061802

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