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Structural Biology of STAT3 and Its Implications for Anticancer Therapies Development

Transcription factors are proteins able to bind DNA and induce the transcription of specific genes. Consequently, they play a pivotal role in multiple cellular pathways and are frequently over-expressed or dysregulated in cancer. Here, we will focus on a specific “signal transducer and activator of...

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Detalles Bibliográficos
Autores principales: Sgrignani, Jacopo, Garofalo, Maura, Matkovic, Milos, Merulla, Jessica, Catapano, Carlo V., Cavalli, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032208/
https://www.ncbi.nlm.nih.gov/pubmed/29843450
http://dx.doi.org/10.3390/ijms19061591