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Inhibition of HIF1α-Dependent Upregulation of Phospho-l-Plastin Resensitizes Multiple Myeloma Cells to Frontline Therapy

The introduction of novel frontline agents in multiple myeloma (MM), like immunomodulatory drugs and proteasome inhibitors, has improved the overall survival of patients. Yet, MM is still not curable, and drug resistance (DR) remains the main challenge. To improve the understanding of DR in MM, we e...

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Detalles Bibliográficos
Autores principales: Bosseler, Manon, Marani, Vanessa, Broukou, Angelina, Lequeux, Amandine, Kaoma, Tony, Schlesser, Vincent, François, Jean-Hugues, Palissot, Valérie, Berchem, Guy J., Aouali, Nasséra, Janji, Bassam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032243/
https://www.ncbi.nlm.nih.gov/pubmed/29882856
http://dx.doi.org/10.3390/ijms19061551

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