Role of Cryptochrome-1 and Cryptochrome-2 in Aldosterone-Producing Adenomas and Adrenocortical Cells

Mice lacking the core-clock components, cryptochrome-1 (CRY1) and cryptochrome-2 (CRY2) display a phenotype of hyperaldosteronism, due to the upregulation of type VI 3β-hydroxyl-steroid dehydrogenase (Hsd3b6), the murine counterpart to the human type I 3β-hydroxyl-steroid dehydrogenase (HSD3B1) gene...

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Detalles Bibliográficos
Autores principales: Tetti, Martina, Castellano, Isabella, Veneziano, Francesca, Magnino, Corrado, Veglio, Franco, Mulatero, Paolo, Monticone, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032245/
https://www.ncbi.nlm.nih.gov/pubmed/29874863
http://dx.doi.org/10.3390/ijms19061675

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