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DNA Damage-Response Pathway Heterogeneity of Human Lung Cancer A549 and H1299 Cells Determines Sensitivity to 8-Chloro-Adenosine

Human lung cancer H1299 (p53-null) cells often display enhanced susceptibility to chemotherapeutics comparing to A549 (p53-wt) cells. However, little is known regarding to the association of DNA damage-response (DDR) pathway heterogeneity with drug sensitivity in these two cells. We investigated the...

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Detalles Bibliográficos
Autores principales:	Yang, Sheng-Yong, Li, Yi, An, Guo-Shun, Ni, Ju-Hua, Jia, Hong-Ti, Li, Shu-Yan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032248/ https://www.ncbi.nlm.nih.gov/pubmed/29843366 http://dx.doi.org/10.3390/ijms19061587

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