Rho GTPases in Intellectual Disability: From Genetics to Therapeutic Opportunities

Rho-class small GTPases are implicated in basic cellular processes at nearly all brain developmental steps, from neurogenesis and migration to axon guidance and synaptic plasticity. GTPases are key signal transducing enzymes that link extracellular cues to the neuronal responses required for the con...

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Detalles Bibliográficos
Autores principales: Zamboni, Valentina, Jones, Rebecca, Umbach, Alessandro, Ammoni, Alessandra, Passafaro, Maria, Hirsch, Emilio, Merlo, Giorgio R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032284/
https://www.ncbi.nlm.nih.gov/pubmed/29925821
http://dx.doi.org/10.3390/ijms19061821

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