Downregulation of α-Melanocyte-Stimulating Hormone-Induced Activation of the Pax3-MITF-Tyrosinase Axis by Sorghum Ethanolic Extract in B16F10 Melanoma Cells

Ultraviolet irradiation-induced hyperpigmentation of the skin is associated with excessive melanin production in melanocytes. Tyrosinase (TYR) is a key enzyme catalyzing the rate-limiting step in melanogenesis. TYR expression is controlled by microphthalmia-associated transcription factor (MITF) exp...

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Detalles Bibliográficos
Autores principales: Lee, Da Hyun, Ahn, Sung Shin, Kim, Jung-Bong, Lim, Yoongho, Lee, Young Han, Shin, Soon Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032395/
https://www.ncbi.nlm.nih.gov/pubmed/29865165
http://dx.doi.org/10.3390/ijms19061640

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032395/
https://www.ncbi.nlm.nih.gov/pubmed/29865165
http://dx.doi.org/10.3390/ijms19061640

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