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Downregulation of α-Melanocyte-Stimulating Hormone-Induced Activation of the Pax3-MITF-Tyrosinase Axis by Sorghum Ethanolic Extract in B16F10 Melanoma Cells

Ultraviolet irradiation-induced hyperpigmentation of the skin is associated with excessive melanin production in melanocytes. Tyrosinase (TYR) is a key enzyme catalyzing the rate-limiting step in melanogenesis. TYR expression is controlled by microphthalmia-associated transcription factor (MITF) exp...

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Detalles Bibliográficos
Autores principales:	Lee, Da Hyun, Ahn, Sung Shin, Kim, Jung-Bong, Lim, Yoongho, Lee, Young Han, Shin, Soon Young
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032395/ https://www.ncbi.nlm.nih.gov/pubmed/29865165 http://dx.doi.org/10.3390/ijms19061640

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