Cargando…

A novel gene-expression-signature-based model for prediction of response to Tripterysium glycosides tablet for rheumatoid arthritis patients

BACKGROUND: Approximately 30% of rheumatoid arthritis (RA) patients treated with Tripterysium glycosides (TG) tablets fail to achieve clinical improvement, implying the essentiality of predictive biomarkers and tools. Herein, we aimed to identify possible biomarkers predictive of therapeutic effects...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Yanqiong, Wang, Hailong, Mao, Xia, Guo, Qiuyan, Li, Weijie, Wang, Xiaoyue, Li, Guangyao, Lin, Na
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032531/ https://www.ncbi.nlm.nih.gov/pubmed/29973208 http://dx.doi.org/10.1186/s12967-018-1549-9

Ejemplares similares

A Novel Circulating miRNA-Based Model Predicts the Response to Tripterysium Glycosides Tablets: Moving Toward Model-Based Precision Medicine in Rheumatoid Arthritis
por: Zhang, Yanqiong, et al.
Publicado: (2018)

Inferences of individual differences in response to tripterysium glycosides across patients with Rheumatoid arthritis using a novel ceRNA regulatory axis
por: Zhang, Yanqiong, et al.
Publicado: (2020)

Clinical Practice Guideline for Tripterygium Glycosides/Tripterygium wilfordii Tablets in the Treatment of Rheumatoid Arthritis
por: Lin, Na, et al.
Publicado: (2021)

Pharmacokinetics-Based Chronoefficacy of Semen Strychni and Tripterygium Glycoside Tablet Against Rheumatoid Arthritis
por: Lin, Jingpan, et al.
Publicado: (2021)

Disease-Modifying Anti-rheumatic Drug Prescription Baihu-Guizhi Decoction Attenuates Rheumatoid Arthritis via Suppressing Toll-Like Receptor 4-mediated NLRP3 Inflammasome Activation
por: Li, Weijie, et al.
Publicado: (2021)

Guizhi-Shaoyao-Zhimu decoction attenuates rheumatoid arthritis partially by reversing inflammation-immune system imbalance
por: Guo, Qiuyan, et al.
Publicado: (2016)

Pathway of PPAR-gamma coactivators in thermogenesis: a pivotal traditional Chinese medicine-associated target for individualized treatment of rheumatoid arthritis
por: Zhang, Yanqiong, et al.
Publicado: (2016)

Correction to: Guizhi-Shaoyao-Zhimu decoction attenuates rheumatoid arthritis partially by reversing inflammation-immune system imbalance
por: Guo, Qiuyan, et al.
Publicado: (2020)

Biomolecular network-based synergistic drug combination discovery: a combination of paeoniflorin and liquiritin alleviates neuropathic pain by inhibiting neuroinflammation via suppressing the chemokine signaling pathway
por: Guo, Qiuyan, et al.
Publicado: (2020)

Integrative network fusion-based multi-omics study for biomarker identification and patient classification of rheumatoid arthritis
por: Ding, Zihe, et al.
Publicado: (2023)

Treatment of Rheumatoid Arthritis Using Combination of Methotrexate and Tripterygium Glycosides Tablets—A Quantitative Plasma Pharmacochemical and Pseudotargeted Metabolomic Approach
por: Wang, Menglei, et al.
Publicado: (2018)

A Discovery of Clinically Approved Formula FBRP for Repositioning to Treat HCC by Inhibiting PI3K/AKT/NF-κB Activation
por: Zhang, Yanqiong, et al.
Publicado: (2020)

Extensive preclinical evaluation of combined mangiferin and glycyrrhizic acid for restricting synovial neovascularization in rheumatoid arthritis
por: Mao, Xia, et al.
Publicado: (2023)

Identification of the Main Active Components and Mechanism of Wang Bi Tablet in Treating Rheumatoid Arthritis Based on Integrative Pharmacology
por: Jiao, Yuanyuan, et al.
Publicado: (2021)

Protocol for rheumatoid arthritis complicated with cardiovascular damage treated with Guanxining tablet with a randomized controlled trial
por: Yu, Kai, et al.
Publicado: (2023)

Uncovering pharmacological mechanisms of Wu-tou decoction acting on rheumatoid arthritis through systems approaches: drug-target prediction, network analysis and experimental validation
por: Zhang, Yanqiong, et al.
Publicado: (2015)

Author Correction: Uncovering pharmacological mechanisms of Wu-tou decoction acting on rheumatoid arthritis through systems approaches: drug-target prediction, network analysis and experimental validation
por: Zhang, Yanqiong, et al.
Publicado: (2018)

Glycyrrhizic Acid Mitigates Tripterygium-Glycoside-Tablet-Induced Acute Liver Injury via PKM2 Regulated Oxidative Stress
por: Wang, Qixin, et al.
Publicado: (2022)

Single-cell transcriptome analysis uncovers underlying mechanisms of acute liver injury induced by tripterygium glycosides tablet in mice
por: Guo, Qiuyan, et al.
Publicado: (2023)

Transcriptome and Lipid Metabolomics-Based Discovery: Glycyrrhizic Acid Alleviates Tripterygium Glycoside Tablet-Induced Acute Liver Injury by Regulating the Activities of CYP and the Metabolism of Phosphoglycerides
por: Shi, Qiaoli, et al.
Publicado: (2022)

Norwegian scabies in a patient treated with Tripterygium glycoside for rheumatoid arthritis
por: Bu, Xiaolin, et al.
Publicado: (2017)

A Novel Drug Combination of Mangiferin and Cinnamic Acid Alleviates Rheumatoid Arthritis by Inhibiting TLR4/NFκB/NLRP3 Activation-Induced Pyroptosis
por: Li, Weijie, et al.
Publicado: (2022)

Tripterygium Glycosides Combined with Leflunomide for Rheumatoid Arthritis: A Systematic Review and Meta-Analysis
por: Yang, Yi-Jing, et al.
Publicado: (2020)

Anti-Angiogenic Effect of Triptolide in Rheumatoid Arthritis by Targeting Angiogenic Cascade
por: Kong, Xiangying, et al.
Publicado: (2013)

Integrated metabolomics and network analysis reveal changes in lipid metabolisms of tripterygium glycosides tablets in rats with collagen-induced arthritis
por: Gao, Yanhua, et al.
Publicado: (2023)

Computational repurposing and preclinical validation of colquhounia root tablets for membranous nephropathy
por: Mao, Xia, et al.
Publicado: (2023)

Effects and Safety of the Tripterygium Glycoside Adjuvant Methotrexate Therapy in Rheumatoid Arthritis: A Systematic Review and Meta-Analysis
por: Geng, Qi, et al.
Publicado: (2022)

An Integrated Glycosylation Signature of Rheumatoid Arthritis
por: Mayboroda, Oleg A., et al.
Publicado: (2023)

Polymorphisms of RAD51B are associated with rheumatoid arthritis and erosion in rheumatoid arthritis patients
por: Zhi, Liqiang, et al.
Publicado: (2017)

A Systems Biology-Based Investigation into the Pharmacological Mechanisms of Wu Tou Tang Acting on Rheumatoid Arthritis by Integrating Network Analysis
por: Zhang, Yanqiong, et al.
Publicado: (2013)

Rheumatoid arthritis characteristics and classification of heat and cold patterns–an observational study
por: Wang, Weijie, et al.
Publicado: (2023)

Monocyte-specific gene signatures in rheumatoid arthritis
por: Grützkau, A, et al.
Publicado: (2004)

Functional Analysis of Autoantibody Signatures in Rheumatoid Arthritis
por: Milchram, Lisa, et al.
Publicado: (2022)

Tanshinone IIA inhibits osteoclastogenesis in rheumatoid arthritis via LDHC-regulated ROS generation
por: Peng, Qiuwei, et al.
Publicado: (2023)

Matrix-mini-tablets of lornoxicam for targeting early morning peak symptoms of rheumatoid arthritis
por: Mohd, Abdul Hadi, et al.
Publicado: (2014)

Thyroid hormone synthesis: a potential target of a Chinese herbal formula Haizao Yuhu Decoction acting on iodine-deficient goiter
por: Zhang, Yanqiong, et al.
Publicado: (2016)

An imprinted rheumatoid arthritis methylome signature reflects pathogenic phenotype
por: Whitaker, John W, et al.
Publicado: (2013)

Impacts of Low-Dose Total Glycosides of Tripterygium wilfordii plus Methotrexate on Immunological Function and Inflammation Level in Patients with Rheumatoid Arthritis
por: Han, Yong, et al.
Publicado: (2022)

A Four-miRNA-Based Diagnostic Signature for Rheumatoid Arthritis
por: Jiang, Xu, et al.
Publicado: (2022)

Molecular Characterization of Circulating Microbiome Signatures in Rheumatoid Arthritis
por: Hammad, Dargham B. M., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_14ha0vc4chs5koglren5ta9bo4