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T-Synthase Deficiency Enhances Oncogenic Features in Human Colorectal Cancer Cells via Activation of Epithelial-Mesenchymal Transition

BACKGROUND: Immature truncated O-glycans such as Tn antigen are frequently detected in human colorectal cancer (CRC); however, the precise pathological consequences of Tn antigen expression on CRC are unknown. T-synthase is the key enzyme required for biosynthesis of mature O-glycans. Here we invest...

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Detalles Bibliográficos
Autores principales:	Dong, Xichen, Jiang, Yuliang, Liu, Jian, Liu, Zhe, Gao, Tianbo, An, Guangyu, Wen, Tao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032660/ https://www.ncbi.nlm.nih.gov/pubmed/30035127 http://dx.doi.org/10.1155/2018/9532389

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